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1.
Journal of Kunming Medical University ; (12): 9-13, 2016.
Article in Chinese | WPRIM | ID: wpr-510734

ABSTRACT

Objective To investigate the relationship between the bacterial vaginosis and 8 putative periodontal pathogen infection.Methods A total of 48 patients with bacterial vaginosis were collected and 47 healthy female patients were selectedin the control group.Vaginal secretion and subgingival plaque were obtained from the study group and the control group.The presence of Porphyromonasgingivalis (P.g),Tannerella forsythia (T.f),Treponemas denticola (T.d),Prevotell intermedia (P.i),Prevotella nigrescen (P.n),Peptostreptococcus micros (P.m),Fusobacteriumnucleatum (F.n) and Campylobacterrectas (C.r) was detected by DNA extraction and PCR method.Simultaneously,all the patients underwent a clinical periodontal examination of the teeth in community periodontal index,including plaque index (PLI),bleeding on probing (BOP),probing depth (PD) and clinical attachment loss (CAL) Results The prevalence of periodontal disease,PLI,BOP and CAL in the study group was significantly higher than in the control group (P<0.05) and the PD had no statistically significant difference between the 2 groups (P>O.05).The 2 groups were both detected 8 putative periodontal pathogens in the vaginal secretion and the subgingival plaque samples.The detection ratio of T.dfrom both the vaginal secretion and subgingival plaque samples was significantly higher in the study group than that in the control group (P <0.05),and other 7 pathogens showed no statistically significant difference (P >0.05) Conclusion The prevalence of periodontal disease was higher among the bacterial vaginosis patients.The 8 putative periodontal pathogens were normal flora in the subgingival plaque and vaginal secretion.Td might be relevant to the pathogenesis of bacterial vaginosis.

2.
West China Journal of Stomatology ; (6): 308-313, 2012.
Article in Chinese | WPRIM | ID: wpr-322396

ABSTRACT

<p><b>OBJECTIVE</b>To make an animal periodontitis and atherosclerosis compound model, and to study the effects of periodontitis on atherosclerosis.</p><p><b>METHODS</b>36 Japan rabbits were randomly divided into four groups: Including periodontitis model group, periodontitis and atherosclerosis compound model group, atherosclerosis model group and control group. Periodontitis model was initiated by ligating floss around teeth cervical and oral inoculating with Porphyromonas gingivalis (P. gingivalis). Atherosclerosis was established by single iliac artery of balloon-injured rabbit. Histopathological change of injured iliac artery was observed under optical microscope after hematoxylin-eosion stain. Elastica van Gieson-stained sections were used for the morphometric analysis. We measured intimal and medial lesion areas in iliac artery cross-sections as well as the intimal/medial ratio (I/M). We also analyzed P. gingivalis 16S rDNA amplification with nested-polymerase chain reaction (nested-PCR), and detect systemic proinflammatory mediators with enzyme linked immunosorbent assay (ELISA), including C-reactive protein (CRP), interleukin-6 (IL-6) and interleukin-1beta (IL-1beta).</p><p><b>RESULTS</b>The serum levels of CRP, IL-6 and IL-1beta increased obviously among the compound model group than other groups (P<0.01). Histopathological observation revealed the compound model group in I/M was bigger than other groups (P<0.01). P. gingivalis 16S rDNA was detected among the periodontitis model group and the compound model group by nested-PCR.</p><p><b>CONCLUSION</b>Periodontitis may accelerate intimal hyperplasia in balloon-injured iliac arteries by upgrade of systemic inflammation factors and local bacterial infection.</p>


Subject(s)
Animals , Rabbits , Animal Experimentation , Atherosclerosis , C-Reactive Protein , Disease Models, Animal , Enzyme-Linked Immunosorbent Assay , Interleukin-6 , Periodontitis , Porphyromonas gingivalis
3.
Journal of Kunming Medical University ; (12)2007.
Article in Chinese | WPRIM | ID: wpr-529485

ABSTRACT

Humanistic spirit advocates the concern for human,and the medical value of people foremost.Now status quo of oral medical students' humanities concern is worrying.This paper aims to analyze the reason,and the best way to culture oral medical students' humanities concern is not only to have an aim of training medical professionals who have oral medical knowledge and skills,but also to look upon the education of medical humanistic spirit as important educative content,to improve teachers' humanities diathesis,to enhance the contact between medical students' and society or patients,to foster affection,to train skills,and to establish the good environment of humanities education.

4.
Journal of Kunming Medical University ; (12)2007.
Article in Chinese | WPRIM | ID: wpr-529484

ABSTRACT

The article discusses how to innovate in the departmental rotation examination for the students practicing in hospital in the new time.It is important for the teacher to provide guidance to students and motivate them to take part in comprehensive training of competence actively so as to cultivate the high-level medical students adaptive to the modern society.

5.
Chinese Journal of Medical Aesthetics and Cosmetology ; (6)2001.
Article in Chinese | WPRIM | ID: wpr-536314

ABSTRACT

Objective To analyse the color ranges of 3 kinds of imported composite resin and to compare the color range of imported composite resin with that of Chinese teeth in the southwest of China. Methods The color of 3 kinds of imported composite resin was mearsured with the spectrophotonery system of human tooth color which had a fiber optic heading.The color range of imported composite resin was compared with that of Chinese teeth. Results The color distribution spaces of 3 kinds of imported compositeresin had different color ranges that were smaller than that of Chinese teeth. Being compared with Chinese teeth color, imported composite resin was short of higher and lower light color, and imported composite resin was short of greener and redder color either. Conclusions The color distribution spaces of imported composite resin are different from that of Chinese teeth in the southwest of China, and any kind of composite resin can not meet the color demand from dental clinic.

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